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Untargeted metabolomics is an unbiased global method that investigates low-molecular-weight metabolites to profile endogenous metabolic alterations resulting from pathological and physiological changes 15,16

Ilic S, Drmic D, Franjic S, Kolenc D, Coric M, Brcic L, Klicek R, Radic B, Sever M, Djuzel V, Filipovic M

doi: 10.1155/2018/1781036 73 KaunaA.OlczykP.Komosiska-VassevK

A., Rinella, M., & Sanyal, A

Each has documented limitations: NSAIDs: Reduce inflammation short-term but inhibit prostaglandin pathways needed for tissue repair